DEVELOPMENT OF A RISK MODEL AND GENOTYPING PATTERNS BASED ON DISULFIDPTOSIS-RELATED LNCRNAS TO PREDICT PROGNOSIS AND IMMUNE LANDSCAPE IN OSTEOSARCOMA

Development of a Risk Model and Genotyping Patterns Based on Disulfidptosis-Related lncRNAs to Predict Prognosis and Immune Landscape in Osteosarcoma

Background: Osteosarcoma (OS) is the most prevalent orthopedic malignancy with a dismal prognosis.Disulfidptosis-related lncRNAs (DRLncs) may be related to the progression of OS, but their potential molecular regulatory role is still unclear.Methods: Based on the data collected from The Cancer Genome Atlas (TCGA), we conducted correlation analysis

read more



Tetraarsenic tetrasulfide triggers ROS-induced apoptosis and ferroptosis in B-cell acute lymphoblastic leukaemia by targeting HK2

Purpose: Acute lymphoblastic leukemia (ALL) is the most common type of cancer diagnosed in children.Despite cure rates of higher than 85 %, refractory or relapsed ALL still exhibits a bleak prognosis indicative of the dearth of treatment modalities specific for relapsed or refractory ALL.Prior research has implicated metabolic alterations in leukem

read more

Molecular identification of Mycoplasma agalactiae from mastitic milk of lactating ewes in Al-Muthana provinceIraq

Mastitis is the main signs of contagious agalactia syndrome in sheep and goats, which is caused by Mycoplasma agalactiae and induces heavy economic losses.The aim of this study was to isolate and identify M.agalactia from mastitic lactating ewes at Al-Muthana province.Clinical mastitic milk collected from infected animals.The collected samples were

read more